Table 3 miRNAs regulated by estrogen/ERα activation

 let-7a-g/i

Located in the intragenic region of an estradiol-regulated gene

[32, 57]

 miR-7

[8, 39]

 miR-9

[131]

 miR-17

ERα-induced MYC/c-MYC upregulation; c-MYC interaction with the miR-17-92 promoter

[32, 39, 57, 59]

 miR-18a

[57]

 miR-19a/b

[8, 57]

 miR-20a

ERα-induced MYC/c-MYC upregulation; c-MYC interaction with the miR-17-92 promoter

[8, 39, 57, 59]

 miR-21

Contains ERα binding sites in regulatory region

[32, 39, 44, 57, 59]

 miR-23a

Contains ERα binding sites in regulatory region

[32]

 miR-24

[132]

 miR-25

[39, 57]

 miR-27b

[39, 67]

 miR-29a

[39]

 miR-30b/c

Located in the intragenic region of an estradiol-regulated gene

[32]

 miR-32

[57]

 miR-34c

[39]

 miR-92a/b

[57, 59, 132]

 miR-93

Requires estrogen metabolism-mediated oxidative stress

[57, 132, 133]

 miR-98

[32, 57]

 miR-99b

[132]

 miR-101

[57]

 miR-103

[32, 132]

 miR-106a/b

[8, 57, 59]

 miR-107

[32]

 miR-124

[39]

 miR-127

[39]

 miR-129

[59]

 miR-148a

[39]

 miR-149

[39]

 miR-181d

[39]

 miR-191

[39, 132]

 miR-196a

Contains ERα binding site in promoter region

[134]

 miR-200a-c

[32, 132]

 miR-203

[32]

 miR-206

[39]

 miR-210

[39]

 miR-301a

[39]

 miR-320a/c

[132]

 miR-424

[32, 57]

 miR-450

[57]

 miR-489

[57]

 miR-503

[135]

 miR-542

[57]

 miR-638

[132]

 miR-1275

[132]

 miR-1915

[132]

 let-7a/c/f/g

Transcriptionally repressed by estradiol-induced ER

[40, 132]

 miR-9

Located in the intragenic region of an estradiol-regulated gene

[32]

 miR-15b

[132]

 miR-21

Mediated by AF-1; Transcriptionally repressed by estradiol-induced ER; Contains ERα binding sites in promoter/regulatory region; Mediated by unliganded ERα

[40,41,42,43,44, 132]

 miR-22

[57, 59]

 miR-23b

Transcriptionally repressed by estradiol-induced ER

[40]

 miR-26a/b

[40, 132]

 miR-27a/b

Contains ERα binding sites in regulatory region; Transcriptionally repressed by estradiol-induced ER

[32, 40, 57]

 miR-127

[59]

 miR-143

[32]

 miR-148a

[136]

 miR-181a/b/d

Contains ERα binding sites in regulatory region; Transcriptionally repressed by estradiol-induced ER; Mediated by unliganded ERα

[40, 57, 137]

 miR-198

[57]

 miR-200c

[40]

 miR-206

[13]

 miR-221/222

Contains ERα binding sites in promoter region

[12]

 miR-302b

[32]

 miR-487b

[57]

 miR-494

[57]

 miR-500

[57]

 miR-506

[32]

 miR-519e

[8]

 miR-524

[32]

 miR-584

[57]

 miR-663

[57]

 miR-671

[57]

 miR-1228

[8]

 miR-1826

[132]