Fig. 4
From: Genetic Manipulation of MicroRNAs in the Silk Gland of Silkworm, Bombyx Mori
Summary of techniques to change the expression of miRNAs. a Up-regulation by miRNA mimic. b Down-regulation by miRNA antagomir. c Overexpression via transgenic technique. d Down-regulation using miRNA sponge. e Knockout through CRISPR/Cas9 system