Fig. 1
From: Mutational Analysis of Ocriplasmin to Reduce Proteolytic and Autolytic Activity in Pichia pastoris

Molecular interactions between S-2403 substrate and amino acids of ocriplasmin presented by 2-D mode. The formed hydrogen bonds among amino acids and substrate presented by green spheres in, a peptide-wild type ocriplasmin, b peptide-proteolytic type ocriplasmin, c peptide-autolytic type ocriplasmin and, d peptide- mixed type ocriplasmin in the docked systems