Your privacy, your choice

We use essential cookies to make sure the site can function. We also use optional cookies for advertising, personalisation of content, usage analysis, and social media.

By accepting optional cookies, you consent to the processing of your personal data - including transfers to third parties. Some third parties are outside of the European Economic Area, with varying standards of data protection.

See our privacy policy for more information on the use of your personal data.

for further information and to change your choices.

Skip to main content
Fig. 2 | Biological Procedures Online

Fig. 2

From: Ultrasound and microbubble-mediated delivery of miR-424-5p has a therapeutic effect in preeclampsia

Fig. 2

Overexpression of miR-424-5p promotes the proliferation, invasion and migration of trophoblast cells. Note: After transfection of miR-424-5p mimic or mimic NC into HTR-8/Svneo and TEV-1 cells, qRT-PCR determined the expression of miR-424-5p in HTR-8/Svneo and TEV-1 cells (A); trophoblast cell proliferation was detected through EdU staining (B); flow cytometry measured cell apoptosis rate (C); the migration and invasion capacities of trophoblast cells were assessed by Scratch assay (D) and Transwell invasion assay (E), respectively; the concentrations of PLGF, β-hCG and TNF-α in the supernatant were examined by ELISA (F). * P < 0.05, **P < 0.01, ***P < 0.001. EdU, 5-Ethynyl-2’-deoxyuridine; PLGF, placental growth factor; β-hCG, human chorionic gonadotropin; TNF-α, tumor necrosis factor-α

Back to article page