Table 1 Cellular component analysis (GO terms) of proteins related to extracellular vesicles or plasma for each of the isolation methods

Extracellular exosome

GO:0070062

195

76.2

2.60E-134

7.99E-131

147

75.4

2.80E-100

9.10E-98

118

75.2

3.20E-80

2.60E-78

Extracellular space

GO:0005615

123

48

2.40E-56

3.10E-54

105

53.8

1.40E-54

1.50E-52

117

74.5

1.00E-84

1.30E-82

Extracellular region

GO:0005576

115

44.9

2.50E-44

2.40E-42

106

54.4

3.00E-51

2.50E-49

113

72

5.50E-74

3.30E-72

Vesicle

GO:0031982

20

7.8

9.4E-13

2.2E-11

15

7.7

1.50E-09

2.60E-08

7

4.5

2.30E-03

1.20E-02

Extracellular vesicle

GO:1,903,561

10

3.9

1.40E-04

1.10E-03

7

3.6

3.50E-03

2.00E-02

5

3.2

3.00E-02

1.20E-01

Plasma membrane

GO:0005886

120

46.9

2.40E-12

5.40E-11

96

49.2

9.20E-12

3.40E-10

81

51.6

1.90E-11

3.30E-10

Blood microparticle

GO:0072562

54

21.1

5.20E-64

9.80E-62

65

33.3

3.80E-93

6.30E-91

83

52.9

1.50E-143

3.60E-141