Fig. 3

CWQ combined with PD-1 inhibitor restores gut dysbiosis in CAC. (A) The ace index, shannon index, and sobs index show significant improvements in gut microbiota diversity with CWQ and PD-1 inhibitor. (B) PCoA reveals gut microbiota reshaping by CWQ combined with PD-1 inhibitor. (C) Rarefaction and shannon curves derived from the sobs index and shannon index. (D) OTU analysis reveals enhanced microbial diversity and abundance with CWQ combined with PD-1 inhibitor. (E) Community barplot analysis among different groups. (F) Community heatmap analysis on genus level among different groups. *P < 0.05, **P < 0.01 and ***P < 0.001