Fig. 1

The construction of a risk-prognosis model associated with telomeres in a HCC cohort. A PCA comparing TCGA HCC tumor and non-tumor groups. B Heatmap displaying the top 100 differentially expressed TRGs in HCC. C Volcano plot highlighting prognostically significant differentially expressed TRGs in HCC. D Determination of the optimal parameter (λ) through LASSO regression analysis. E Spectrum of LASSO regression coefficients for 18 telomeric-associated genes