Fig. 3

Single-cell RNA sequencing analysis of HCC. A Examination of single-cell RNA sequencing in HCC tissue shows that all cells are grouped into 9 distinct subclusters, as illustrated in the UMAP plot. B Heatmap of the correlation between the marker gene and 5 cell types. C The cells have been labeled as NKT cells, hepatocytes, HPC-like cells, macrophages, and B cells, among several others. D Following the scoring of TRGs, a UMAP visualization map depicting cell distribution was generated. E A visual heat map depicting the expression patterns of 18 crucial TRGs across five distinct cell types