Table 1 MR analysis between the serum proteins and gastric cancer

ANGPT2

IVW

3

1.237967

1.012798

1.513197

0.037146

WM

3

1.250323

1.022977

1.528195

0.029119

CMX

3

1.248392

1.022097

1.52479

0.033899

RAPS

3

1.238098

1.005547

1.52443

0.044208

CML

3

1.257924

1.025378

1.543211

0.027785

ATRAID

IVW

4

1.212607

1.03508

1.420581

0.01699

WM

4

1.204338

1.035513

1.400687

0.015828

CMX

4

1.207221

0.793201

1.837344

0.036957

RAPS

4

1.21263

1.029518

1.42831

0.020982

CML

4

1.218395

1.045441

1.419962

0.011441

BPIFA2

IVW

4

1.267962

1.077349

1.4923

0.004285

WM

4

1.269901

1.068451

1.509333

0.006702

CMX

4

1.27623

1.087531

1.497669

0.014417

RAPS

4

1.268111

1.069868

1.503087

0.006169

CML

4

1.268943

1.070719

1.503865

0.005987

CD6

IVW

5

1.094775

1.014596

1.181289

0.019626

WM

5

1.092063

1.008907

1.182073

0.029299

CMX

5

1.100093

1.020604

1.185772

0.019802

RAPS

5

1.094786

1.012421

1.183852

0.023247

CML

5

1.096445

1.023597

1.174478

0.008667

CFHR2

IVW

8

0.881709

0.782562

0.993418

0.038593

WM

8

0.870578

0.766652

0.988592

0.032606

CMX

8

0.876676

0.781439

0.983519

0.03067

RAPS

8

0.881678

0.779882

0.996762

0.04424

CML

8

0.877214

0.78106

0.985205

0.026992

CPQ

IVW

7

0.913336

0.854432

0.976301

0.007696

WM

7

0.92595

0.865608

0.990499

0.025243

CMX

7

0.911187

0.853844

0.972382

0.010943

RAPS

7

0.913964

0.855532

0.976386

0.007609

CML

7

0.912878

0.855187

0.97446

0.006205

FUT8

IVW

11

1.095717

1.008827

1.190091

0.030122

WM

11

1.102352

1.006036

1.20789

0.036708

CMX

11

1.092611

1.003576

1.189544

0.031656

RAPS

11

1.096305

1.006632

1.193966

0.034702

CML

11

1.094364

1.006043

1.190438

0.035699

HCG22

IVW

5

1.21034

1.113601

1.315483

7.07E-06

WM

5

1.227636

1.12874

1.335198

1.70E-06

Weighted mode

5

1.232938

1.130462

1.344703

0.009105

CMX

5

1.227536

1.138838

1.323141

0.0281

RAPS

5

1.189549

1.038463

1.362617

0.012259

CML

5

1.208416

1.110203

1.315317

1.20E-05

IGLC2

IVW

3

1.184369

1.026401

1.366648

0.020515

WM

3

1.185185

1.018519

1.379123

0.027998

CMX

3

1.179265

0.886824

1.568142

0.027545

RAPS

3

1.184611

1.021124

1.374274

0.025359

CML

3

1.171643

1.023443

1.341305

0.021685

LILRB1

IVW

6

1.068684

1.003525

1.138075

0.038487

WM

6

1.069275

1.001277

1.141891

0.04571

CMX

6

1.072795

1.015384

1.133451

0.040952

RAPS

6

1.068637

1.001716

1.140028

0.044223

CML

6

1.067976

1.001793

1.138531

0.043916

LTB

IVW

3

0.58721

0.487637

0.707115

1.96E-08

WM

3

0.586423

0.484015

0.710497

5.02E-08

Weighted mode

3

0.585794

0.474364

0.723398

0.038211

CMX

3

0.589425

0.489873

0.709207

0.004067

RAPS

3

0.587387

0.482098

0.715672

1.30E-07

CML

3

0.596916

0.490633

0.726223

2.50E-07

MATN3

IVW

10

1.226676

1.052813

1.429252

0.008794

WM

10

1.268021

1.080553

1.488014

0.003624

Weighted mode

10

1.273617

1.099481

1.475333

0.010417

CMX

10

1.268927

1.103152

1.459614

0.006639

RAPS

10

1.235358

1.069757

1.426595

0.003999

CML

10

1.217932

1.039678

1.426749

0.014608

NELL1

IVW

3

1.088776

1.018655

1.163723

0.012273

WM

3

1.086132

1.01676

1.160236

0.014144

CMX

3

1.091571

0.930175

1.28097

0.048089

RAPS

3

1.088795

1.016751

1.165945

0.014867

CML

3

1.081554

1.00911

1.1592

0.026667

NMNAT1

IVW

3

0.592072

0.377728

0.928049

0.022276

WM

3

0.5666

0.359952

0.891883

0.014115

CMX

3

0.392471

0.18263

0.843417

0.041813

RAPS

3

0.555679

0.339417

0.909736

0.019485

CML

3

0.589432

0.388516

0.894249

0.012934

PBLD

IVW

7

0.871089

0.775334

0.978669

0.020184

WM

7

0.865938

0.767581

0.9769

0.019287

CMX

7

0.858413

0.717007

1.027707

0.019847

RAPS

7

0.869869

0.771535

0.980736

0.022738

CML

7

0.86946

0.774337

0.976268

0.017967

PPCDC

IVW

4

1.051053

1.004623

1.099629

0.030767

WM

4

1.050914

1.00476

1.099187

0.030215

CMX

4

1.05158

1.010347

1.094496

0.030776

RAPS

4

1.051065

1.003359

1.101039

0.035596

CML

4

1.049212

1.003481

1.097026

0.034616

RGMA

IVW

5

1.192546

1.026764

1.385095

0.021118

WM

5

1.220296

1.03532

1.43832

0.017603

CMX

5

1.189192

1.028677

1.374752

0.021135

RAPS

5

1.192789

1.021582

1.392687

0.02574

CML

5

1.190167

1.031353

1.373435

0.017196

TLR3

IVW

5

1.122208

1.032818

1.219335

0.006479

WM

5

1.111641

1.017812

1.21412

0.018652

CMX

5

1.118002

1.037219

1.205077

0.012751

RAPS

5

1.122272

1.030372

1.22237

0.008136

CML

5

1.120465

1.036026

1.211786

0.004436

TNFRSF10C

IVW

4

1.158701

1.024385

1.310629

0.019116

WM

4

1.156886

1.019727

1.312493

0.023611

CMX

4

1.150841

1.015614

1.304074

0.023917

RAPS

4

1.158733

1.020768

1.315345

0.022738

CML

4

1.142781

1.00511

1.299308

0.041567

TNFRSF11A

IVW

7

0.866977

0.787085

0.954979

0.003805

WM

7

0.861642

0.769322

0.965041

0.010012

Weighted mode

7

0.860199

0.770547

0.96028

0.03645

CMX

7

0.859676

0.777867

0.950089

0.013005

RAPS

7

0.866838

0.784587

0.957711

0.004962

CML

7

0.864705

0.784859

0.952674

0.003274

TNFSF12

IVW

4

0.699216

0.534849

0.914093

0.008871

WM

4

0.707939

0.534841

0.937059

0.01576

CMX

4

0.697711

0.323049

1.506892

0.03717

RAPS

4

0.699759

0.531034

0.922093

0.011207

CML

4

0.718468

0.550283

0.938056

0.0151