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Table 1 The basic character of the patients in this study cohort

From: Negative Regulation of Cell Adhesion as a Driver of Brain Metastasis in NSCLC Patients with EGFR Amplification

Characteristic

Cohort one

n (%)

Cohort two

n (%)

Tissue type

Brain Metastases

Lung Cancer

Number

30

24

Age (year)

Median

55.5

59

Range

37–76

45–72

Gender

Female

16 (53)

11 (46)

Male

14 (47)

13 (54)

Driver oncogene

  

EGFR

13

16

L858R

4 (13)

6 (25)

19del

5 (17)

9 (38)

L861Q

2 (7)

1 (4)

G719A

1 (3)

 

G719S

1 (3)

 

KRAS

5 (17)

3 (12)

ALK

3 (10)

 

RET

1 (3)

 

BRAF

1 (3)

 

Wild Type

4 (13)

5 (20)

Diagnose of BM/lung cancer

Pathology

30 (100)

24 (100)

Histologic type

  

Adenocarcinoma

26 (87)

21 (87)

Squamous

4 (13)

3 (13)