Fig. 2
From: PRRG4 Brain-Specific Conditional Knockout Mice Display Autism Spectrum Disorder-Like Behaviors
Male and female PRRG4-CKO mice exhibit social behavior deficits. A Movement trajectory diagrams of male and female PRRG4fl/fl and PRRG4-CKO mice during the social ability test stage. B, C Statistical analysis of the time spent contacting the S1 cage and the E cage by male (B) and female (C) PRRG4fl/fl and PRRG4-CKO mice during the social ability test stage. D Statistical analysis of the social ability index, social ability index = time spent contacting S1 cage/(time spent contacting S1 cage + time spent contacting E cage). E Movement trajectory diagrams of male and female PRRG4fl/fl and PRRG4-CKO mice during the social novelty test stage. F, G Statistical analysis of the time spent contacting the S1 cage and the S2 cage by male (F) and female (G) PRRG4fl/fl and PRRG4-CKO mice during the social novelty test stage. H Statistical analysis of the social novelty index, social novelty index = time spent contacting S2 cage/(time spent contacting S2 cage + time spent contacting S1 cage). Note: the numbers of experimental mice in each group (10–11 mice/group) were indicated on the bar. S1 or S2: mouse S1 or S2, E: empty; ***: p < 0.001, **: p < 0.01, *: p < 0.05, ns: no significant statistical difference